2006 IBEST Bioinformatics Workshop
August 14th, 15th, & 16th
Workshop Target
Dr. Celeste Brown,
Bioinformatics Coordinator and Matt Settles,
Ph.D. student in Bioinformatics and Computational Biology are
presenting this 3 day workshop series as an
introduction to the analysis of biological data and their
interpretation. The focus of the workshop will be on the use of the IBEST
computing facilities and the analysis of sequence data and
microarray experiments. Material will be available for self-study.
Participants should have some minimal
background in biological, statistical and computational aspects of
genetic sequences if attending the first day, and microarrays or
other high-throughput data if attending the second day.
Workshop Focus
The focus will be on analyzing and
interpreting sequence data and microarray data. The first day
of the workshop will provide an introduction to the IBEST computing
facilities and sequence analysis. The second day of the workshop is
an introduction to microarray analysis. The third and final day of
the workshop gives the participants an opportunity to bring their
own data and apply the tools learned in days 1 and 2.
Workshop Agenda
Location
University of Idaho
Janssen
Engineering Building (JEB) 211a
Registration
Registration is free. Registration for the workshop is
limited to the first 23 registrants due to available computer
resources. Registration for the lunch events is
unlimited. Please indicate which days you will attend and if
you will be attending the lunch events.
Registration for the Workshop is Closed. - Please
feel free to register for the lunch events if you wish to attend a
lunch.
Registration Form
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Lunch Event Details
Tuesday’s Sponsored Lunch – S-PLUS® and S+ArrayAnalyzer -
Insightful Corporation
Dr. David Henderson – Research Scientist Insightful Corp.
Insightful Corporation is a leading provider of scalable data and text
analysis solutions that drive better decisions faster by integrating
statistics into business processes. Based on the flexible S language, the
S-PLUS® product family delivers leading solutions for exploratory data
analysis and statistical modeling, enabling analysts and researchers to
perform more insightful analyses, create revealing graphics, and make more
informed decisions.
Discovery researchers in many biopharmaceutical companies are using
S+ArrayAnalyzer for analyzing microarray data. Gene expression
microarrays are a powerful experimental platform for studies of functional
genomics, toxicogenomics, cancer subtyping and a host of other applications.
Differential expression analysis is a key analysis component in most
studies. A major goal of such analyses is to identify genes that are
differentially expressed between experimental conditions, while keeping the
probability of false discoveries acceptably low. Given the many sources of
variability in microarray measurements, the need for experimental design,
replication and statistically rigorous pre-processing and differential
expression analysis is now widely recognized. S+ArrayAnalyzer
includes many components for design, data access, data preparation
(probe-level analysis, normalization etc.), differential expression testing,
FDR/FWER correction and interactive visualization and annotation of results.
Wednesday’s Sponsored Lunch – GeneChip® technology -
Affymetrix Inc.
Mark Daly – Affymetrix Senior Account Manager
Affymetrix' GeneChip® microarray technology was invented in the late
1980's by a team of scientists lead by Stephen P.A. Fodor, Ph.D. The theory
behind their work was revolutionary - a notion that semiconductor
manufacturing techniques could be united with advances in combinatorial
chemistry to build vast amounts of biological data on a small glass chip.
This technology became the basis of a new company, Affymetrix. Affymetrix’
mission is to be the leading source of molecular technologies to understand
and improve life. With many new advances in the world of microarray
technologies. |
